王文平教授团队于Advance Science杂志发表论文:Nano Ultrasound Contrast Agent for Synergistic Chemo-photothermal Therapy and Enhanced Immunotherapy Against Liver Cancer and Metastasis
本文报道了一种纳米超声造影剂(arsenictrioxide (ATO)/PFHNPs@Au-cRGD)用于增强肝癌化学免疫治疗并监测治疗效果。该造影剂与PD-L1抗体联合使用,可有效抑制肝脏原位肿瘤,并通过激活全身免疫抑制肺转移,为未来研究解决肝癌治疗的临床需求奠定了基础,并可能对肝癌以外的其他实体瘤的治疗产生影响。
QiuY, Wu Z, Chen Y, et al. Nano Ultrasound Contrast Agent forSynergistic Chemo-photothermal Therapy and Enhanced ImmunotherapyAgainst Liver Cancer and Metastasis. AdvSci.2023;10(21):e2300878. doi:10.1002/advs.202300878